MPHI’s Center for Child and Family Health (CCFH) implements a variety of strategies to identify children who are most at risk of abuse and neglect and to improve the systems that serve these children and families. Through partnerships with national, state, and local experts, CCFH staff create positive systemic changes that improve the safety of children in their homes and communities. CCFH staff facilitate Michigan’s Citizen Review Panel on Child Fatalities (CRPCF). The CRPCF submits recommendations to Michigan’s child protection system based on findings from in-depth case reviews conducted by a multidisciplinary panel of Michigan’s leading child maltreatment prevention experts. CCFH staff also play a key role in an innovative demonstration project, Reducing Child Fatalities and Recurring Child Injuries Caused by Crime Victimization (Child Safety Forward/CSF). The goals of CSF are to better identify children who are at the most risk for maltreatment; to improve cross-sector collaboration; to increase public awareness around the risk factors for and signs of possible child maltreatment with strategic messaging that reinforces the shared role of family, community members, and professionals in the identification and prevention of child maltreatment; and to increase access to direct services for victims of child maltreatment and to support services for at risk families.